597997 Disclosed is a composition comprising: a combination of antibodies that specifically binds to at least five polypeptides having molecular weights of 88 kDa, 55 kDa, 38 kDa, 37 kDa, 36 kDa, 35 kDa, or 33 kDa, wherein molecular weight is determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel, wherein the polypeptides are isolatable from a Staphylococcus aureus when incubated in media comprising an iron chelator and not isolatable when grown in the media without the iron chelator, and wherein the composition protects an animal against challenge with S. aureus ATCC strain 19636.
