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AGENT FOR INHIBITING PERITONEAL MEMBRANE THICKENING
专利权人:
Hironobu Murase;Tadashi Tomo
发明人:
Hironobu Murase,Tadashi Tomo
申请号:
US13259558
公开号:
US20120083461A1
申请日:
2010.03.30
申请国别(地区):
US
年份:
2012
代理人:
摘要:
PROBLEMThe present invention is directed to provide a thickening inhibitory agent for inhibiting peritoneal membrane thickening which enables inhibition/prevention or treatment of the peritoneal membrane thickening and which mitigates adverse effect, and a dialysis fluid comprising the aforementioned thickening inhibitory agent.SOLUTIONThe above-described problem is solved by means of an agent for inhibiting peritoneal membrane thickening, comprising as an effective ingredient a chromanol glycoside represented by the following chemical formula (1):(in this regard, however, R1, R2, R3, and R4 each represent a hydrogen atom or a lower alkyl group which may be the same as or different from each other; R5 represents a hydrogen atom, a lower alkyl group or a lower acyl group; X represents a mono-sugar residue or an oligo-sugar residue in which a hydrogen atom of hydroxyl group in sugar residue may be substituted by a lower alkyl group or a lower acyl group; n is an integer of 0 to 6; and m is an integer of 1 to 6), or a dialysis fluid comprising the same.
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