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SYSTEM AND METHOD FOR DYNAMIC MULTIPLE CONTRAST ENHANCED, MAGNETIC RESONANCE FINGERPRINTING (DMCE-MRF)
专利权人:
Case Western Reserve University
发明人:
Chris Flask,Christian Anderson,Xin Yu,Nicole Steinmetz,Mark A. Griswold,Susann Brady-Kalnay
申请号:
US16603335
公开号:
US20200041595A1
申请日:
2018.04.06
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure provides a method of DDCE-MRF. The method can include: a) introducing two or more contrast agents to a region of interest (ROI) of a subject, the two or more contrast agents having different relaxivities; b) measuring a T1 relaxation time and a T2 relaxation time for locations within the ROI using magnetic resonance fingerprinting (MRF); c) determining, using equations that relate the different relaxivities, the T1 relaxation time, the T2 relaxation time, and concentrations of the two or more contrast agents, the concentrations of the two or more contrast agents for each of the locations within the ROI; and d) producing an image depicting the ROI based, at least in part, on the concentrations of the two or more contrast agents.
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