您的位置: 首页 > 农业专利 > 详情页

ANTI-TNF ALFA ANTIKŪNAI, SKIRTI PANAUDOTI TERAPIJOJE
专利权人:
AbbVie Biotechnology Ltd
发明人:
Kempeni, Joachim,Weiss, Roberta,Fischkoff, Steven A.
申请号:
LT15165133
公开号:
LT2940044T
申请日:
2002.06.05
申请国别(地区):
LT
年份:
2017
代理人:
摘要:
Methods of treating disorders in which TNF± activity is detrimental via biweekly, subcutaneous administration of human antibodies, preferably recombinant human antibodies, that specifically bind to human tumor necrosis factor ± (hTNF ±) are disclosed. The antibody may be administered with or without methotrexate. These antibodies have high affinity for hTNF± (e.g., K d = 10 -8 M or less), a slow off rate for hTNF± dissociation (e.g., K off = 10 -3 sec -1 or less) and neutralize hTNF± activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Kits containing a pharmaceutical composition and instructions for dosing, and preloaded syringes containing pharmaceutical compositions are also encompassed by the invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充