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DEVICE AND METHODS OF USING DEVICE FOR DETECTION OF HYPERAMMONEMIA
专利权人:
发明人:
Omar Bilal Ayyub,Adam Michael Behrens,Peter Kofinas,Marshall Lynn Summar, II,Juan Manuel Cabrera-Luque,Gary Cunningham
申请号:
US15570269
公开号:
US20180143210A1
申请日:
2016.04.27
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present disclosure relates to a biosensor capable of measuring the total concentration of one or a plurality of ammonia or ammonium ions with the use of indophenol reagents in the presence of an ionomer. In some embodiments, the biosensor comprises a perflurinated membrane that comprises an ionomer in contact with an alkali buffer in a vessel configured to receive a sample, such as whole blood. The disclosure also relates to a method of detecting or quantifying the ammonia or ammonium ion concentration in whole blood in a point of care bio sensor without reliance on gas chromatography or any measurement that takes more than about twenty minutes.
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