Adolfo Garcia-Sastre,Peter Palese,Florian Krammer,Natalie Pica,Dirk Eggink,Rafael A. Medina-Silva,Rong Hai
申请号:
US14345816
公开号:
US20150132330A1
申请日:
2012.09.19
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Provided herein are flu hemagglutinin polypeptides, including chimeric influenza virus hemagglutinin polypeptides, and flu hemagglutinin polypeptides comprising modified glycosylation sites and non-naturally glycosylation sites, compositions comprising the same, vaccines comprising the same and methods of their use.