A medical waste fluid collection cart may include one or more sensors, a controller in communication with at least one of the sensors, and a memory coupled to the controller, the memory configured to store one or more algorithms, measurement correlations, and/or look-up tables relating sensed measurements to concentrations of waste fluid received from a surgical site. The fluid collection cart may further include a container and a suction tube having a lumen extending through the suction tube, where the suction tube may communicate with the container to deposit waste fluid from a surgical site in the container. One or more of the sensors may include a light sensor for sensing a measure related to a concentration of blood in the waste fluid removed from a surgical site. The controller may determine a blood loss quantity from identifying an average blood concentration in the waste fluid removed from the surgical site.