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Novel calcium salts of compound as anti-inflammatory, immunomodulatory and anti-proliferatory agents
专利权人:
4SC AG
发明人:
AMMENDOLA ALDO,DIEDERICHS JULIA,LEBAN JOHANN,VITT DANIEL
申请号:
NZ60501011
公开号:
NZ605010A
申请日:
2011.07.01
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
IP No. 605010 The present disclosure relates to calcium salts of compounds of the general formula (I) wherein X is selected from the group consisting of CH, S, or O D is O or S R is hydrogen or alkyl E is an optionally substituted phenylene group Y is a monocyclic or bicyclic substituted or unsubstituted 6-9 membered ring system which may contain one or more heteroatoms selected from N or S and which contains at least one aromatic ring n is 0 or 1, and q is 0 or 1 with the proviso that compounds wherein X = CH, q =0, Y unsubstituted phenyl and E = unsubstituted phenylene are excluded or a hydrate thereof. A particular compound salt of the disclosure is the calcium salt of 2-[(3-Fluoro-3&rsquo-methoxy-4-biphenylyl)carbamoyl]-1-cyclopentene-1-carboxylic acid also known as vidofludimus.
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