Klaus Fortschegger;Regina Grillari;Johannes Grillari;Elisabeth Schraml
发明人:
Johannes Grillari,Elisabeth Schraml,Klaus Fortschegger,Regina Grillari
申请号:
US13699272
公开号:
US20130108687A1
申请日:
2011.05.23
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compositions of an inhibitor of a polynucleotide for use in treating or preventing bone disorders such as osteoporosis, osteopenia, bone fracture, bone cancer, as well as impaired bone homeostasis. Preferred compounds to be used in these medical interventions are antagonistic compounds, like nucleic acid molecules, directed against miR-31 and derivatives thereof. Also, methods for diagnosing and compositions for use in diagnosing bone disorders. Compounds to be employed in these diagnostic methods and uses include compounds such as miR-31.