Non-peptidyl, potent, and selective mu opioid receptor antagonists and their use in treating opioid addiction and opioid induced constipation

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专利权人:

发明人:

Yan Zhang,Dana E. Selley,William Dewey

申请号：

US14287254

公开号：

US08980908B2

申请日:

2014.05.27

申请国别(地区):

US

年份:

2015

代理人:

摘要：

Selective, non-peptide antagonists of the mu opioid receptor (MOR) and methods of their use are provided. The antagonists may be used, for example, to identify MOR agonists in competitive binding assays, and to treat conditions related to addiction in which MOR is involved, e.g. heroin, prescription drug and alcohol addiction, as well as in the treatment of opioid induced constipation (OIC).

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中国工程科技知识中心

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http://www.ckcest.cn/home/