PROBLEM TO BE SOLVED: To provide anti-inflammatory agents, moisturizing agents, therapeutic agents and external preparations for atopic dermatitis which contain a vitamin B6 derivative and give a sufficient effect to skin inflammation and dryness without causing skin irritation.SOLUTION: The invention relates to anti-inflammatory agents, moisturizing agents, therapeutic agents and external preparations for atopic dermatitis which contain the compound represented by formula (1), or a salt thereof. (Where, R1 represents a glycosyl group, a phosphate group, or a cyclic phosphoric acid group bound to R2 R2 represents a -CH2OH, -CHO, -CH2 NH2, -CH2-amino acid residue or -CH2-OPO2H and R3 represents a hydrogen atom or -PO3H2.)COPYRIGHT: (C)2016,JPO&INPIT【課題】ビタミンB6誘導体を含有し、皮膚刺激がなく、皮膚の炎症や乾燥に対して充分な効果が得られる抗炎症剤、保湿剤、アトピー性皮膚炎の治療剤及び外用剤を提供すること。【解決手段】式(1)で表される化合物又はその塩を含有する抗炎症剤、保湿剤、アトピー性皮膚炎の治療剤及び外用剤。(式中、R1はグリコシル基、リン酸基、又はR2と結合した環状リン酸基を示し、R2は-CH2OH、-CHO、-CH2NH2、-CH2-アミノ酸残基、又は-CH2-OPO2Hを示し、R3は水素原子又は-PO3H2を示す。)【選択図】なし