Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
WILKINSON, H. SCOTT,CARON, JUDY,LALJI, KARIM,VARNEY, MARK,HAN, ZHENGXU,KOENIG, STEFAN G.,SINGH, SURENDRA P.,WESSEL, THOMAS,SU, XIPING,BAKALE, ROGER P.
申请号:
AU2012202991
公开号:
AU2012202991B2
申请日:
2012.05.22
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl- 1 napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders.