PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF LIVER TOXICITY DISEASE COMPRISING SOCHEONGRYONG-TANG OR LACTIC ACID BACTERIA FERMENTED SOCHEONGRYONG-TANG
MA, JIN YEUL,마진열,OH, SU YOUNG,오수영,SEO, SANG HEE,서상희,LEE, JI SEON,이지선,LEE, JI HYE,이지혜
申请号：
KR1020110135353
公开号：
KR1020130068317A
申请日:
2011.12.15
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A composition containing socheongryong tang(kind of oriental medicine) and lactic acid bacteria-fermented socheongryong tang is provided to protect liver cells from cytotoxicity due to oxidative stress and tBHP, and to be used as a pharmaceutical composition or a health functional food for preventing and treating disorders by hepatotoxicity. CONSTITUTION: A pharmaceutical composition for preventing and treating disorders by hepatotoxicity contains socheongryong tang and/or lactic acid bacteria-fermented socheongryong tang. The lactic acid bacteria are selected from the group consisting of Bipidobacterium, Lactobacillus, Streptococcus, Leuconostoc, Pediococcus, and Lactococcus. A method for preparing the fermented socheongryong tang comprises: a step of mixing crude drug materials including Ephedrae herba, Paeonia lactiflora, Asarum sieboldii, Zingiberis rhizoma, Glycyrrhiza uralensis fischer, Cinnamomi ramulus, Pinellia ternate, and Schisandra chinensis (Turcz.) Baill, and extracting by hot water to prepare socheongryong tang； a step of inoculating lactic acid bacteria mycelium to socheongryong tang and preparing a culture liquid； and a step of fermenting the culture liquid. A health functional food for preventing and treating disorders by hepatotoxicity contains socheongryong tang and/or lactic acid-fermented socheongryong tang.본 발명은 소청룡탕 및 소청룡탕의 유산균 발효물을 포함하는 조성물에 관한 것으로, 구체적으로 소청룡탕 및 소청룡탕에 유산균을 접종, 배양, 발효시켜 제조한 소청룡탕의 유산균 발효물이 간 독성에 대하여 간세포 보호작용을 하는 효과를 가지는 간독성 질환 예방 및 치료용 약학적 조성물에 관한 것이다.
