Brown University;Massachusetts Institute of Technology
发明人:
Brown Tyler C.,Moore Christopher I.
申请号:
US201715633143
公开号:
US10149986(B2)
申请日:
2017.06.26
申请国别(地区):
美国
年份:
2018
代理人:
Clark & Elbing LLP
摘要:
The invention features methods for regulating vascular properties by controlling the membrane properties of endothelial cells using optogenetics and light. The invention features methods to transport therapeutics across the vascular barrier into tissues such as the brain and the lung, with high spatial and temporal precision, and for controlling vascular properties such as vascular tone, arterial diameter, and vascular growth.