Stephen M. G. Gottschalk,LaTerrica C. Williams,Tiara T. Byrd,Nabil M. Ahmed,Xiao-Tong Song
申请号:
US14773434
公开号:
US20160015750A1
申请日:
2014.03.10
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Embodiments of the invention provide for cell therapy for cancers having a TEM1 or TEM8 antigen. Certain embodiments provide for cell therapy that targets tumor vasculature, including the tumor vascular bed, for example. In specific embodiments, TEM1- and/or TEM8-specific chimeric antigen receptors are employed.