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Phosphine transition metal complex, process for producing same, and anticancer agent
专利权人:
Hiroaki Kodama
发明人:
Hiroaki Kodama,Keisuke Ohto,Nobuhiko Oohara,Kazuhiro Nakatsui,Yoshirou Kaneda
申请号:
US12302517
公开号:
US08278303B2
申请日:
2007.05.31
申请国别(地区):
US
年份:
2012
代理人:
摘要:
An anticancer agent having a novel chemical structure and high anticancer activity is provided. A phosphine transition metal complex of general formula (1) and an anticancer agent containing the complex are disclosed.R1 and R2, which may be the same or different, each represent a group having 1 to 10 carbon atoms selected from a straight-chain or branched alkyl group, a cycloalkyl group, a substituted cycloalkyl group, an adamantyl group, a phenyl group, and a substituted phenyl group R3 and R4, which may be the same or different, each represent a hydrogen atom, a straight-chain alkyl group having 1 to 6 carbon atoms or branched alkyl group having 1 to 6 carbon atoms or R3 and R4 are taken together to form a saturated or unsaturated ring which may have a substituted group M represents a transition metal atom selected from the group consisting of gold, copper, and silver and X− represents an anion.
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