Jae-Kwan Hwang,Do-Un Kim,Jae-Youn Chung,Hee-Chul Chung,Kyu-Lee Han
申请号：
US12766255
公开号：
US08853264B2
申请日:
2010.04.23
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to the use of lignan compounds for treating or preventing an inflammatory disease. More particularly, it relates to a method for preventing or treating an inflammatory disease, comprising administering to a subject in need thereof an effective amount of macelignan represented by Chemical Formula I or a pharmaceutically acceptable salt thereof. The lignan compound has the effect of inhibiting inflammatory reactions by inhibiting the production or expression of inflammation mediators NO, iNOS, PGE2, COX-2 and TNF-α and by treating or preventing inflammatory disease in vivo. Accordingly, the lignan compound or a Myristica fragrans extract will be highly useful for the treatment or prevention of an inflammatory disease.
