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BIOMATERIALS FOR COMBINED RADIOTHERAPY AND IMMUNOTHERAPY OF CANCER
专利权人:
NORTHEASTERN UNIVERSITY
发明人:
NGWA, WILFRED,KUMAR, RAJIV,MAKRIGIORGOS, GERASSIMOS,SRIOHAR, SRINIVAS,DOUGAN, STEPHANIE
申请号:
CA2995372
公开号:
CA2995372A1
申请日:
2016.08.15
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Compositions and methods for the radiological and immunotherapeutic treatment of cancer are provided. Metallic nanoparticles conjugated with an immunoadjuvant are dispersed within a biodegradable polymer matrix that can be implanted in a patient and released gradually. The implant may be configured as, or be a component of, brachytherapy spacers and applicators, or radiotherapy fiducial markers. The composition may be combined with marginless radiotherapy, allowing for lower doses of radiation and enhancing the immune response against cancer, including at non-irradiated sites.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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