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FABRICATION METHOD FOR STRATIFIED AND LAYERED TISSUE TO REPAIR OSTEOCHONDRAL DEFECTS
专利权人:
发明人:
Corey P. Neu,Tyler A. Novak,Garrett Shannon
申请号:
US14194207
公开号:
US20140242140A1
申请日:
2014.02.28
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Fabrication method for stratified and layered tissue to repair osteochondral defects. In a method of the present disclosure, the method comprises the step of applying a first direction magnetic field to a first quantity of a first collagen solution to align collagen within the first collagen solution in a first direction relative to the first direction magnetic field, forming a first layer of collagen. In a method of generating an aligned collagen layer of the present disclosure, the method comprises applying a first magnetic field at or greater than 0.1 Tesla to a layer of a first collagen solution defining a horizontal plane, within a temperature at or between 2° C. and 45° C., to generate an aligned collagen layer.
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