NOUVEAUX RADIOIMMUNOCONJUGUES QUI LIENT LA CD37 HUMAINE

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专利权人:

NORDIC NANOVECTOR AS

发明人:

LARSEN, ROY H.,DAHLE, JOSTEIN,BRULAND, OYVIND S.

申请号：

CA2786655

公开号：

CA2786655C

申请日:

2011.01.28

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The present invention relates to a radioimmunoconjugate that binds human CD37comprising a) an anti-CD37 antibody comprising an immunoglobulin heavy chainand an immunoglobulin light chain, wherein the heavy chain comprises the aminoacid sequence of SEQ ID NO: 2 and the light chain comprises the amino acidsequence of SEQ ID NO: 4； b) a chelating linker； and c) a radionuclideselectedfrom the group consisting of 177Lu, 225Ac, 227Th, 212Pb and 90Y.

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