Dan Keil;Thomas Plocher;Todd Johnson;Trent Harbison;Richard Harland;Manuel Campos
发明人:
Thomas Plocher,Manuel Campos,Richard Harland,Todd Johnson,Trent Harbison,Dan Keil
申请号:
US12934654
公开号:
US09046528B2
申请日:
2009.03.20
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Compositions and methods for determining immunologically cross-reactive molecules comprising a cross-reactive antigenic determinant are provided, in particular for determining proteins comprising cross-reactive antigenic determinants, in particular for determining proteins that are cross-reactive based on serological screens using sequential immunological challenges to an animal, including determining cross-reactive H. parasuis proteins. Also provided are compositions, vaccines, and kits using the molecules for diagnostics and methods for preventing or treating a disease, disorder, condition, or symptoms thereof associated with infectious agents, in particular infectious microorganisms, in particular for preventing or treating a disease, disorder, condition, or symptom thereof associated with H. parasuis infection.