PHARMACEUTICAL MANUFACTURING RESEARCH SERVICES; INC.
发明人:
THOMPSON, EDWIN R.,THOMPSON, ERIC R.,MYSLINSKI, NICHOLAS R.,KEMENY, STEVEN F.
申请号：
CA2934078
公开号：
CA2934078C
申请日:
2014.12.17
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present disclosure relates to an oral, extended release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogeneously spread throughout a matrix used to deter abuse. The pill can be prepared using a hot melt extrusion process and a forming unit. The formed pill meets regulatory guidelines for extended release formulations and is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.
