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POCHODNE PIRYDAZYNONOWE
- 专利权人:
- Merck Patent GmbH
- 发明人:
- DORSCH DIETER,STIEBER FRANK,SCHADT OLIVER,BLAUKAT ANDREE
- 申请号：
- PL14001269
- 公开号：
- PL2754660T3
- 申请日:
- 2008.04.29
- 申请国别(地区):
- PL
- 年份:
- 2017
- 代理人:
- 摘要：
- The compound is new. The compound of formula (I), their pharmaceutical useful derivatives, solvate, salts, tautomers and stereoisomers, are new. For formula (I), R 1>； : Ar, benzo-2,1,3-thiadiazolyl or Het, where Ar is selected from phenyl, naphthyl or biphenyl, which are unsubstituted or once, twice or thrice substituted by hal, A, N(R 3>；) 2, [C(R 3>；) 2] nOR 3>；, [C(R 3>；) 2] nN(R 3>；) 2, SR 3>；, NO 2>；, CN, COOR 3>；, CON(R 3>；) 2, NR 3>；COA, NR 3>；SO 2A, SO 2N(R 3>；) 2, S(O) mA, CO-Het, Het, O[C(R 3>；) 2] nN(R 3>；) 2, O[C(R 3>；) 2] nHet, NHCOOA, NHCON(R 3>；) 2, NHCOO[C(R 3>；) 2] nN(R 3>；) 2, NHCOO[C(R 3>；) 2] nHet, NHCONH[C(R 3>；) 2] nN(R3)2, NHCONH[C(R 3>；) 2] nHet, OCONH[C(R 3>；) 2] nN(R3)2, OCONH[C(R 3>；) 2] nHet, CONR 3>；[C(R 3>；) 2] nN(R 3>；) 2, CONR 3>；[C(R 3>；) 2] nHet or COA, and Het is once, twice or thrice saturated or unsaturated or aromatic heterocycles with 1-4 N-, O- or S-atoms or piperidinyl, piperazinyl, pyrrolidinyl, morpholinyl, furyl, thienyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, pyridyl, pyrimidinyl, triazolyl, tetrazolyl, oxadiazolyl, thiadiazolyl, pyridazinyl, pyrazinyl, benzimidazolyl, benzotriazolyl, indolyl, benzo[1,3]dioxolyl, indazolyl, azabicyclo[3.2.1]octyl, azabicyclo[2.2.2]octyl, imidazolidinyl, azepanyl or benzo [2,1,3]thiadiazolyl, which are unsubstituted or once, twice or thrice substituted by halide, A, [C(R 3>；) 2] nOR 3>；, [C(R 3>；) 2] nN(R 3>；) 2, SR 3>；, NO 2>；, CN, COOR 3>；, CON(R 3>；) 2, NR 3>；COA, NR 3>；SO 2A, SO 2N(R 3>；) 2, S(O) mA, CO-Het 1>；, [C(R 3>；) 2] nHet 1>；, O[C(R 3>；) 2] nN(R 3>；) 2, O[C(R 3>；) 2] nHet 1>；, NHCOOA, NHCON(R 3>；) 2, NHCOO[C(R 3>；)2] nN(R 3>；) 2, NHCOO[C(R 3>；) 2] nHet 1>；, NHCONH[C(R 3>；) 2] nN(R 3>；) 2, NHCONH[C(R 3>；) 2] nHet 1>；, OCONH[C(R 3>；) 2] nN(R 3>；) 2, OCONH[C(R 3>；) 2] nHet 1>；, [C(R 3>；) 2] nOR 3>；, [C(R 3>；) 2] nNR
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
