Various exemplary surgical attachmentes are provided with drug by activator material. In general, there is attachment at least one drug to be arranged to be activated, by activator material. The attachment can be conveyed to tissue of patient, can be implanted into attached. Various activator materials may be configured to activate at least one described drug retaine by attached, and activation leads to any one or more of movement. For example, at least one drug can be activated and generate at least one signal and/or influence auxiliary agent.