An injection device including a needle protection system, comprising a discharge needle (10) having a discharge port (11), wherein the needle protection system protects the discharge port (11) of the discharge needle (10) in a non-discharge position. In order to isolate, it comprises a movable needle protection member (20) disposed on the discharge needle (10), the needle protection member (20) includes an isolation part (21) formed of a flexible material, At the discharge position, the discharge port (11) of the discharge needle (10) is pierced by the isolation part (21), and the diameter of the needle protection member (20) protruding outward in at least one radial direction. A directional protrusion (25), the protection system further comprising an outer cap member (30) provided with grip means (35, 35 ', 36; 38; 300), the grip means comprising the needle Less protective member (20) In addition, the outer cap member (30) is moved in a direction away from the discharge port (11) in the longitudinal direction of the discharge needle (10) in cooperation with one radial protrusion (25), thereby moving the needle from the non-discharge position. The protective member (20) is removed, the at least one radial protrusion (25) is disposed at the axial end of the needle protection member (20), and the at least one radial protrusion (25) is Formed on the rigid outer structure (28) of the needle protection member (20). [Selection] Figure 2針保護システムを含む注射装置であって、吐出口(11)を有する吐出針(10)を含み、前記針保護システムが、非吐出位置において吐出針(10)の吐出口(11)を保護し隔離するために、吐出針(10)に配される移動可能な針保護部材(20)を備え、前記針保護部材(20)は柔軟な材料で形成された隔離部(21)を含み、非吐出位置において、吐出針(10)の吐出口(11)が、前記隔離部(21)に突き刺されるようになっており、前記針保護部材(20)が少なくとも一つの径方向外側へ突出する径方向突出部(25)を備え、前記保護システムは、さらに、グリップ手段(35、35’、36;38;300)が設けられた外側キャップ部材(30)を備え、このグリップ手段は、前記針保護部材(20)の少なくとも一つの径方向突出部(25)と協働し、外側キャップ部材(30)を吐出針(10)の長手方向の吐出口(11)から離れる方向に移動させることにより、非吐出位置から針保護部材(20)を除去し、前記少なくとも一つの径方向突出部(25)は、針保護部材(20)の軸方向末端部に配され、前記少なくとも一つの径方向突出部(25)は、針保護部材(20)の堅い外側構造物(28)に形成される。【選択図】図2