Philip Felgner;Maria Laura Gennaro;David Huw Davies;Xiaowu Liang
发明人:
Philip Felgner,David Huw Davies,Xiaowu Liang,Maria Laura Gennaro
申请号：
US12447620
公开号：
US09297803B2
申请日:
2007.11.01
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Contemplated compositions, devices, and methods comprise immunodominant antigens from selected human pathogens (Burkholderia pseudomallei, Borrelia burgdorferi, Brucella melitensis, Chlamydia muridarum, Coxiella burnetii, Francisella tularensis, human Herpes virus 1 and 2, Mycobacterium tuberculosis, Plasmodium falciparum, and Vaccinia virus) can be used as a vaccine, as diagnostic markers, and as therapeutic agents. In particularly preferred aspects, the antigens have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and have a known association with a disease parameter.
