ＨＣＶ／ＧＢＶ−Ｂキメラウイルス
- 专利权人:
- 发明人:
- 申请号：
- JP20100520878
- 公开号：
- JP5693957(B2)
- 申请日:
- 2009.07.15
- 申请国别(地区):
- 日本
- 年份:
- 2015
- 代理人:
- 摘要：
An HCV/GBV-B chimeric virus which maintains the replication function of HCV and is capable of infecting tamarin is disclosed in order to construct an HCV animal model which can be used as a development or evaluation system for therapeutic agents for HCV. The HCV/GBV-B chimeric RNA comprises an RNA of hepatitis C virus and an RNA of GB virus-B, wherein the RNA of hepatitis C virus comprises an RNA encoding leucine at the 1804th position and lysine at the 1966th position in the amino acid sequence of the polyprotein of hepatitis C virus.
- 来源网站：
- 中国工程科技知识中心
