The present invention relates to a novel family of protein kinase inhibitors, more specifically the present invention is directed to inhibitors of the members of the Tec or Src protein kinase families. The present invention also relates to the processes of preparation of these compounds, their intermediates, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative, inflammatory, autoimmune, or infectious diseases, disorders, or conditions in which protein kinase activity is implicated.本發明與蛋白質激酶抑制劑之一新穎家族有關,詳細而言本發明係針對Tec或Src蛋白質激酶家族成員之抑制劑。本發明亦與若干化合物及其中間物之製備方法有關,與包含前述化合物及其中間物之醫藥組成物有關,以及與前述醫藥組成物在涉及蛋白質激酶活性之增生性、發炎性、傳染性或自體免疫性疾病、失調或狀況治療中之使用有關。