The invention described herein includes a repellent elastomeric article with antimicrobial properties particularly useful in industrial and medical fields, such as gloves. The article contains an elastomeric base and a fluid-repellent coating composition that effectively repels both hydrophilic and lipophilic liquids from its surface and inhibits cross-contamination of surfaces. Articles prepared in accordance with the invention reduce the risk of contamination associated with blood and other body fluids, as well as reduce fluid-based visual obstruction and enhance the clarity of medical procedures. The invention also provides a method of reducing the ability of fluids to adhere to the surface of an elastomeric article.