Invention is related to replace 5,6- dihydro -6- phenyl benzos [F] isoquinolin -2- amine compounds and the method that synthesizes such compound. The present invention also relates to containing be substituted 5,The pharmaceutical composition of 6- dihydros -6- phenyl benzo [F] isoquinolin -2- amine compounds and the method for giving such compound and pharmaceutical composition to the individual for the treatment of in need to treat cell proliferative disorder (such as cancer).發明涉及取代的5,6-二氫-6-苯基苯并[F]異喹啉-2-胺化合物及合成該類化合物的方法。本發明也涉及含有經取代的5,6-二氫-6-苯基苯并[F]異喹啉-2-胺化合物的藥物組合物及對有需要治療的個體給予該類化合物及藥物組合物以治療細胞增生性病症(例如癌症)的方法。