The present disclosure discloses a collimator, a radiotherapy device and a control driving method thereof, belonging to the medical technical field. The collimator is applied to a radiotherapy device, the radiotherapy device includes a plurality of radioactive sources, a plurality of collimating hole groups are arranged on the collimator, and an included angle of each collimating hole group in the longitudinal direction is within a preset included angle range. Each of the collimating hole groups includes a plurality of collimating holes, and beams emitted from the plurality of radioactive sources intersect at a common focus after passing through each collimating hole of the collimating hole group. The collimator, the radiotherapy device and the driving control method thereof can protect sensitive tissues and organs during treatment.
