Jack J. Hawiger,Ruth Ann Veach,Yan Liu,Huan Qiao,Lukasz S. Wylezinski
申请号：
US16448960
公开号：
US20200046799A1
申请日:
2019.06.21
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to compositions and methods for preventing and reducing inflammation and preventing and treating diseases and disorders associated with inflammation. It has been shown that CRADD plays a pivotal role in maintaining the integrity of endothelial monolayers. The recombinant cell-penetrating CRADD protein (CP-CRADD)-based compositions and methods described herein provide for the development of a novel treatment for inflammatory vascular disorders including cardiovascular, cerebrovascular, respiratory, gastrointestinal, and renal systems.
