Heather Fairhead,Adam Wilkinson,Sarah Holme,Katy Pitts,Alison Jackson
申请号:
US15147483
公开号:
US10106784B2
申请日:
2016.05.05
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided is a modified bacteriophage capable of infecting a target bacterium, which bacteriophage includes an α/β small acid-soluble spore protein (SASP) gene encoding a SASP which is toxic to the target bacterium, wherein the SASP gene is under the control of a constitutive promoter which is foreign to the bacteriophage and the SASP gene.