Eddy Jean Edgard Freyne,Kristof Van Emelen,Peter Jacobus Johannes Antonius Buijnsters,Timothy Pietro Suren Perera,Werner Constant Johan Embrechts
申请号：
BRPI0417609
公开号：
BRPI0417609B1
申请日:
2004.12.15
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
"3-cyano-quinoline derivatives with antiproliferative activity". The present invention relates to the compounds of formula (I) n-oxide forms, pharmaceutically acceptable addition salts and stereochemically isomeric forms thereof. Compounds of formula (I) inhibit tyrosine kinase enzymes."derivados de 3-ciano-quinolina com atividade antiproliferativa". a presente invenção diz respeito aos compostos de fórmula (i) as formas n-óxido, os sais de adição farmaceuticamente aceitáveis e as formas estereoquimicamente isoméricas dos mesmos. compostos de fórmula (i) inibem enzimas tirosina quinase.
