Massachusetts Institute of Technology ;Raytheon BBN Technologies, Corp.
发明人:
Kiani Samira,Weiss Ron,Beal Jacob S.,Ebrahimkhani Mohammad Reza,Xie Zhen,Li Yinqing
申请号:
US201615146653
公开号:
US2016326546(A1)
申请日:
2016.05.04
申请国别(地区):
美国
年份:
2016
代理人:
摘要:
Provided herein, in some embodiments, are modular transcriptional architectures and methods for regulated expression of guide RNAs in cells, such as human cells, which are based on Clustered Regularly Interspaced Palindromic Repeats (CRISPR) systems.