THE REGENTS OF THE UNIVERSITY OF MICHIGAN;PHRIXUS PHARMACEUTICALS, INC.
发明人:
NG, RAINER,METZGER, JOSEPH M.,REEVE, LORRAINE,MARKHAM, BRUCE
申请号:
CA2708761
公开号:
CA2708761C
申请日:
2008.12.17
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention relates to compositions and methods for treating andpreventing skeletal muscle deficiencies.In particular, the present invention provides compositions comprisingpoloxamers (e.g., poloxamer 188 - P188) and methods ofusing the same for treating and preventing skeletal muscle deficiencies andinjuries (e.g., dystrophin-deficient skeletal muscle;skeletal muscle having a contraction force deficit; skeletal muscle having aCa2+ imbalance; skeletal muscle having microtears).