The method involves filling exposure bag with supplement to less than thirty percent volume of the maximum volume of the exposure bag for photodynamic treatment or irradiation with ultra-violet light. The exposure bag is moved during the photo-dynamic treatment or the irradiation with ultravoilet light, so that contents of the exposure bag are rolled and zones of changing layer thicknesses are formed by the movement. The photoactive substance is a phenotiazines dyestuff, particularly thionin, methylene blue, phthalocyanine, phorphyrin and toluidine blue.본 발명은 격렬한 교반을 이용하여 유연성 노출백 안에서 광역학적 처리 및/또는 자외선 조사에 의해 헌혈자의 혈액, 혈액혈장 및 적혈구 농축액 안의 박테리아 및 바이러스와 같은 병원체를 불활성화하기 위한 방법에 관한 것이다.