The present invention relates to the field of medicinalization I-science, specifically a class of chemical I-compounds containing lactams and derivatives thereof, in particular pyridine derivatives represented by the general formula (I), preparation methods and factor Xa inhibition Relates to its use as an agent. The invention further relates to the medical use of compounds I-compounds and derivatives thereof for the preparation of anticoagulant drugs, in particular for the preparation of drugs for the prevention or treatment of thrombosis or embolism. Embedded image本発明は、医薬品化Ｉ－学の分野、具体的にはラクタム及びその誘導体を含有する化Ｉ－合物のクラス、特に一般式（Ｉ）に示されるピリジン誘導体、調製方法並びに第Ｘａ因子阻害剤としてのその使用に関する。本発明は更に、抗凝固薬物の調製への化Ｉ－合物及びその誘導体の医学的使用、特に血栓症又は塞栓症を予防又は治療するための薬物の調製への使用に関する。 【化Ｉ－１】
