Jeffrey Lester BROWN,Stephen Charles Emery,David Charles Blakey
申请号:
US13952997
公开号:
US20140023654A1
申请日:
2013.07.29
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention relates to agents which possess anti-angiogenic activity and are accordingly useful in methods of treatment of disease states associated with angiogenesis in the animal or human body. More specifically the invention concerns a combination of an antagonist of the biological activity of Angiopoietin-2 and an antagonist of the biological activity of VEGF-A, and/or KDR, and/or Flt1, and uses of such antagonists.