GOMEZ SEBASTIAN SILVIA,GOMEZ SEBASTIAN SILVIA,LÓPEZ VIDAL JAVIER,LÓPEZ VIDAL JAVIER,MARTINEZ ESCRIBANO JOSÉ ANGEL,MARTINEZ ESCRIBANO JOSÉ ANGEL
申请号:
PL12753914
公开号:
PL2858490T3
申请日:
2012.06.12
申请国别(地区):
PL
年份:
2017
代理人:
摘要:
Reagents and methods are provided that allow for an improved expression of a recombinant protein in an insect More specifically, the introduction of recombinant DNA elements into an insect larva allows for the increased expression of a recombinant protein, an improvement of the correct folding of said protein and an increase in the survival rate after infection of the insect These recombinant DNA elements can be introduced, for example, into insect larvae via a recombinant baculovirus, which has incorporated said elements. The recombinant DNA elements include nucleic acids encoding transcriptional regulators, such as IE-0 and lE-1, transcriptional enhancer elements, such as the homologous region (hr) and promoters.