Ana Del Pozo Rodriguez;Alicia Rodriguez Gascôn;Diego Delgado San Vicente;José Luis Pedraz Mu{umlaut over (n)}oz;Maria Angeles Solinís Aspíazu
发明人:
Alicia Rodriguez Gascôn,Maria Angeles Solinís Aspíazu,Ana Del Pozo Rodriguez,Diego Delgado San Vicente,José Luis Pedraz Mu{umlaut over (n)}oz
申请号：
US13386611
公开号：
US09675710B2
申请日:
2010.07.27
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to a lipid nanoparticle system comprising a lipid component, a cationic surfactant, a non-ionic surfactant, a polysaccharide and, optionally, a positively charged peptide, useful for the release of pharmacologically active molecules, and especially for transfecting genetic material into cells and/or tissues. It also relates to methods for obtaining nanoparticles, to pharmaceutical compositions comprising it, as well as to the use thereof in gene therapy.
