Inc.;Emory University;Dana-Farber Cancer Institute;Dana-Farber Cancer Institute, Inc.
发明人:
AHMED, Rafi,GREGSON, James, P.,FREEMAN, Gordon, J.,JONES, Timothy, D.,CARR, Francis, J.
申请号：
DK09816950
公开号：
DK2342226T3
申请日:
2009.09.25
申请国别(地区):
DK
年份:
2016
代理人:
摘要：
The present invention is based, in part, on the identification of novel human anti-PD-1, PD-L1, and PD-L2 antibodies. Accordingly, the invention relates to compositions and methods for diagnosing, prognosing, and treating conditions that would benefit from modulating PD-1, PD-L1, and/or PD-L2 activity (e.g., persistent infectious diseases, autoimmune diseases, asthma, transplant rejection, inflammatory disorders and tumors) using the novel human anti-PD-1, PD-L1, and PD-L2 antibodies described herein.
