Karina Yusim,Bette T. M. Korber,Carla L. Kuiken,William M. Fischer
申请号:
US12893731
公开号:
US08460672B1
申请日:
2010.09.29
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention relates to immunogenic compositions useful as HCV vaccines. Provided are HCV mosaic polypeptide and nucleic acid compositions which provide higher levels of T-cell epitope coverage while minimizing the occurrence of unnatural and rare epitopes compared to natural HCV polypeptides and consensus HCV sequences.