Xiaozhang Zheng,Pui Yee Ng,Bingsong Han,Jennifer R. Thomason,Mary-Margaret Zablocki,Cuixian Liu,Aleksandra Rudnitskaya,David R. Lancia, Jr.,David S. Millan,Matthew W. Martin
申请号:
US16220049
公开号:
US10494353B2
申请日:
2018.12.14
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present disclosure relates to inhibitors of zinc-dependent histone deacetylases (HDACs) useful in the treatment of diseases or disorders associated with an HDAC, e.g., HDAC6, having a Formula I:where R, L, X1, X2, X3, X4, Y1, Y2, Y3, and Y4 are described herein.