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NUCLEAR MAGNETIC RESONANCE DIAGNOSTIC AGENT, AND METHOD FOR DETECTING OR DIAGNOSING STATE OF CELL, TISSUE OR ORGAN IN SUBJECT USING SAME
专利权人:
National University Corporation Kumamoto University;University of Occupational and Environmental Health, Japan;SBI Pharmaceuticals Co., Ltd.
发明人:
Tetsuya YONEDA,Shigeru NISHIZAWA,Junkoh YAMAMOTO,Tohru TANAKA,Hidenori ITOH
申请号:
US14650530
公开号:
US20150320888A1
申请日:
2013.12.09
申请国别(地区):
US
年份:
2015
代理人:
摘要:
[Problem]To provide a nuclear magnetic resonance diagnostic agent that has a lower toxicity to organisms and reduced side effects and yet has a site specificity toward a specific cell, tissue, organ, etc.[Solution]When ALA or an ALA derivative is administered in vivo, a metabolite thereof is accumulated in a specific cell, tissue, organ, etc. Focusing on this phenomenon, a nuclear magnetic resonance analysis was performed on a site wherein the metabolite of ALA that had been administered in vivo would be possibly accumulated. As a result, it was surprisingly found that ALA and an ALA derivative are useful as a diagnostic agent whereby the aforesaid problem can be solved.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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