Sendurai A. MANI,Brett G. HOLLIER,Kurt W. EVANS,Steven J. WERDEN,Tapasree Roy SARKAR,Agata TINNIRELLO
申请号：
US14205770
公开号：
US20140275201A1
申请日:
2014.03.12
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides biomarkers of cancer stem cells, as well as cells that have undergone EMT. In addition, the present invention provides methods of treating patients determined to comprise cancer stem cells with PDGFR-β inhibitors to eliminate the cancer stem cells. Methods of predicting sensitivity to PDGFR-β inhibitors, monitoring efficacy of treatment, and determining a prognosis are also provided.
