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SMALL MOLECULE ANTI-SCARRING AGENTS
专利权人:
UNIVERSITY OF ROCHESTER
发明人:
Richard P. Phipps,Collynn Woeller
申请号:
US15319254
公开号:
US20170216332A1
申请日:
2015.06.16
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Disclosed are methods of treating fibrosis in a patient in need thereof that includes administering to the patient an amount of an active agent, as identified herein, that is therapeutically effective to inhibit myofibroblast formation and thereby treat the fibrosis. Also disclosed is a recombinant cell line that includes a recombinant gene that expresses a detectable expression product in a dose-dependent response to TGFβ, as well as methods of identifying a compound that inhibits TGFβ-mediated expression of the detectable expression product.
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中国工程科技知识中心
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