The present invention relates to a compound of the formulain all its isomeric forms and pharmaceutically acceptable salts thereof, their manufacture, pharmaceutical compositions containing them and their use as medicaments for the treatment and/or prophylaxis of diseases which can be treated with HDL-cholesterol raising agents, such as preferably dyslipidemia, atherosclerosis and cardiovascular diseases.本發明係關於一種下式化合物呈其所有異構形式,及其醫藥上可接受鹽,其製造,包含其之醫藥組合物,及其作為藥劑之用途,用於治療及/或預防可用HDL-膽固醇升高劑治療之疾病,諸如較佳為血脂異常、動脈粥樣硬化及心血管疾病。