PROBLEM TO BE SOLVED: To provide an agent for preventing and/or treating a periodontal disease or a dental caries disease which has excellent autoinducer-2 inhibitory activity, and is effective for preventing and treating the periodontal disease or the dental caries disease.SOLUTION: The agent for preventing and/or treating the periodontal disease and/or the dental caries disease contains at least one kind of compound having a partial structure represented by formula (1) and a glucose residue in the molecule, and in which the hexahydrodiphenoyl group part of the partial structure represented by the formula (1) is substituted at position 4 and position 6 of the glucose residue or the salt thereof as an active ingredient.【課題】優れたオートインデューサー-2阻害活性を有し、歯周病又は齲蝕病の予防及び治療に有効な、歯周病又は齲蝕病の予防及び/又は治療剤を提供することを目的とする。【解決手段】分子内に式(1)で表される部分構造及びグルコース残基を有し、該グルコース残基の4位と6位に式(1)で表される部分構造のヘキサヒドロジフェノイル基部分が置換した少なくとも1種の化合物又はその塩を有効成分とする、歯周病又は齲蝕病の予防及び/又は治療剤。【選択図】なし