Soren Nielsen;Jorgen Frokiaer;Bjarne Due Larsen;Thomas E. N. Jonassen
发明人:
Thomas E. N. Jonassen,Soren Nielsen,Jorgen Frokiaer,Bjarne Due Larsen
申请号：
US12064923
公开号：
US08466104B2
申请日:
2005.08.26
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention describes peptide analogues of a-melanocyte-stimulating hormone (a-MSH), which posses an increased efficacy compared to the native α-MSH peptide. The α-MSH analogues exhibit increased anti-inflammatory effects and increased capability to prevent ischemic conditions compared to α-MSH. The invention further discloses use of the peptides for the manufacture of pharmaceutical compositions for the treatment or prophylaxis of a condition in the tissue of one or more organs of a mammal, and moreover pharmaceutical compositions.
